Can 嫩草影院 effectively curb the symptoms of Parkinson鈥檚 disease and slow its progression?
Evidence from studies is promising.
Scientists have discovered a link between a dysfunctional endocannabinoid system (ECS) and the development of Parkinson鈥檚 disease. According to research, 嫩草影院 (or cannabidiol) may help with the management of the condition, including the non-motor symptoms.
Being diagnosed with Parkinson鈥檚 doesn鈥檛 mean you can鈥檛 live a productive and happy life. Taking 嫩草影院 oil can help you improve your quality of life without the nasty side effects associated with prescription medications.
Moreover, 嫩草影院 doesn鈥檛 get you high like marijuana. And while traditional medications may lose efficacy over time, 嫩草影院 typically provides long-lasting benefits.
Don鈥檛 get us wrong, 嫩草影院 isn鈥檛 a miracle drug. It won鈥檛 cure Parkinson鈥檚 disease or any medical disease for that matter. However, high-quality Cannabidiol oil can improve your daily life with Parkinson鈥檚.
嫩草影院 is making big headlines in mainstream media, and for a good reason. It offers a wide range of health benefits, including relief from anxiety, epilepsy, pain, insomnia, and neurodegenerative conditions.
In this article, we鈥檒l help you understand the effects of 嫩草影院 on Parkinson鈥檚. We鈥檝e also prepared a buyer鈥檚 guide for beginners and our list of the best 嫩草影院 brands whose products actually work.
Best 嫩草影院 Oils for Parkinson鈥檚 disease in 2022
1. (Overall Winner)
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Why We Recommend Royal 嫩草影院 Oil for Parkinson鈥檚 Disease
Royal 嫩草影院 offers full-spectrum 嫩草影院 oil made from organically grown hemp from farms in Colorado. The oil is available in four different concentrations, including 250 mg, 500 mg, 1000 mg, and 2500 mg. The guys at Royal 嫩草影院 have also created three flavored versions of their oil: Mint, Vanilla, and Berry. These are naturally flavored oils that cater to those who don鈥檛 like holding natural 嫩草影院 oil in their mouth.
As mentioned, these are full-spectrum products, so you鈥檙e getting synergistic effects from 嫩草影院, other cannabinoids, terpenes, and flavonoids. This phenomenon is known as the 鈥渆ntourage effect鈥� 鈥� it鈥檚 also the reason why full-spectrum products are the preferred option among consumers.
The oil is suspended in premium-grade MCT oil for higher bioavailability and a milder taste. The 2500 mg bottle may be helpful for non-motor symptoms like irritation, fatigue, or anxiety. This 嫩草影院 also works well for easing physical discomfort.
All of Royal 嫩草影院鈥檚 products are CO2-extracted and tested in a third-party laboratory for potency and purity. The company also has a 30-day money-back guarantee program.
2. (Best Organic)
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Why We Recommend Gold Bee for Parkinson鈥檚 Disease
Gold Bee is a California-based brand that makes 100% organic products. This means that every ingredient in its 嫩草影院 oil 鈥� from hemp to flavorings 鈥� comes from organic sources. Although the company doesn鈥檛 have any high-strength oils in its line up, the lower potencies still provide full-spectrum 嫩草影院 and the desired entourage effect. This is a great brand for beginners and those who don鈥檛 take more than 40 mg 嫩草影院 daily.
We love how Gold Bee 嫩草影院 oils taste. The kiwi flavor, which is sweetened with honey, has won our hearts; this is the best-tasting 嫩草影院 oil we鈥檝e got so far. Similar to Royal 嫩草影院, Gold Bee uses supercritical CO2 extraction and tests its products in a certified laboratory.
3. 嫩草影院istillery (Runner Up)
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Why We Recommend 嫩草影院istillery 嫩草影院 Oil for Parkinson鈥檚 Disease
嫩草影院istillery is one of the pioneer companies on the market. It offers both full-spectrum and broad-spectrum 嫩草影院 oils. The broad-spectrum version is labeled as 鈥減ure oil鈥� and includes all non-psychoactive cannabinoids, terpenes, and flavonoids 鈥� but without any THC. This type of 嫩草影院 oil caters to people who would like to benefit from the entourage effect (to some extent) with no THC in their product. Unlike other companies in this ranking, this one doesn鈥檛 have any flavored oils.
The best thing about 嫩草影院istillery in relation to Parkinson鈥檚 disease is the potency range of these 嫩草影院 oils. You can choose from as little as 250 mg to a whopping 5000 mg of 嫩草影院 per bottle. Even if you don鈥檛 use 嫩草影院 oil to manage severe symptoms, such concentrations can get you stocked up for months to come.
Speaking of which, 嫩草影院istillery is also one of the most affordable companies on the market.
4. 嫩草影院Pure (Good Value)
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Why We Recommend 嫩草影院Pure 嫩草影院 Oil for Parkinson鈥檚 Disease
嫩草影院Pure specializes in making low-to-moderate potency 嫩草影院 oils that contain the full-spectrum of cannabinoids. These oils are available in four concentrations: 100 mg, 300 mg, 600 mg, and 1000 mg 嫩草影院 per bottle. This company is a great choice for users who already have experience with 嫩草影院 but their dosage doesn鈥檛 go beyond 30 mg daily. If you value transparency and are looking for an artisan-grade formula, 嫩草影院Pure should meet your expectations.
5. Charlotte鈥檚 Web (Best Variety)
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Why We Recommend Charlotte鈥檚 Web 嫩草影院 Oil for Parkinson鈥檚 Disease
Charlotte鈥檚 Web was founded by the Stanley Brothers who are also responsible for the global 嫩草影院 rush. The brothers have helped a young girl (now late) Charlotte Figi reduce her seizure attacks from several a day to one case a week 鈥� introducing the anti-epileptic properties of 嫩草影院 to a broader public. Charlotte鈥檚 Web uses olive oil to extract its 嫩草影院 oils, which is thought to be inferior to CO2 but more 鈥渘atural.鈥� The unique extraction method, along with a broad selection of high-quality products, has made Charlotte鈥檚 Web one of the most recognizable brands in the industry.
What is Parkinson鈥檚 Disease?
Parkinson鈥檚 Disease (PD) is a neurological disease that involves the degeneration of a person鈥檚 nervous system, with an average onset at the age of 60. Simply put, brain cells that release the neurotransmitter dopamine become damaged and start to degrade.
This can trigger an array of motor problems, such as tremors, problems with balance, stiffness in joints and muscles, and lack of facial expression.
On top of that, Parkinson鈥檚 Disease may also result in Parkinson鈥檚 disease dementia (PDD), which negatively impacts a person鈥檚 cognitive functioning, such as the ability to pay attention, make decisions, or remember things.
Sometimes, PDD is confused with Lewy Bodies Dementia (LBD). However, with the latter, cognitive impairment occurs before motor issues. Both conditions are progressive, so the symptoms will get worse over time, and alas, there鈥檚 no therapy that could cure people out of PD.
Overview of Parkinson鈥檚 Disease Symptoms
The first symptoms of Parkinson鈥檚 Disease aren鈥檛 severe and include:
- The slowness of movement (Bradykinesia)
- Balance problems
- Lack of facial expression
- Difficulty sitting or standing.
Parkinson鈥檚 disease patients experience issues with walking as the disease develops. There鈥檚 also a medical term known as Parkinsonian gait. People with this condition have a stooped posture, limited arm movement, and shuffle their feet.
Other symptoms of PD include:
- Compromised judgment
- Constipation
- Delusions
- Difficulty maintaining focus
- Loss of smell
- Memory loss
- Slurred speech
- Trouble swallowing
- Visual hallucinations
Patients with Parkinson鈥檚 disease may also suffer from apathy, anxiety, irritability, depression, pain, and insomnia. Many people also develop Parkinson鈥檚 dementia over time, as mentioned above.
How is Parkinson鈥檚 Disease Treated?
Doctors usually recommend prescription medications to make the symptoms of Parkinson鈥檚 disease manageable. Unfortunately, these medications only provide short-term relief and may require larger doses to produce the desired effects. This, in turn, may result in a range of side effects such as blurred vision, nausea, vomiting, diarrhea, heartburn, dry mouth, loss of appetite, drowsiness, lightheadedness, and more.
Lethal overdose is another serious risk of conventional treatments for Parkinson鈥檚 disease.
How Does 嫩草影院 Oil Help with Parkinson鈥檚 Disease?
Doctors may not use 嫩草影院 oil for Parkinson鈥檚 disease long-term, which is not surprising considering that research into the effects of 嫩草影院 for this condition only started a few decades ago. Nevertheless, the current findings are very promising. Studies have found some positive effects of 嫩草影院 on certain symptoms of Parkinson鈥檚 disease, especially when it comes to non-motor symptoms, such as anxiety, depression, and insomnia.
Below we shed more light on the health benefits of 嫩草影院 oil for Parkinson鈥檚 disease patients.
嫩草影院 May Lower Tremors
Common medications for Parkinson鈥檚 disease can lead to drug-induced tremors and uncontrolled muscle twitches. Long-term use of such medicine could even worsen this symptom. One older conducted on a small group of subjects suggested that 嫩草影院 may potentially treat these tremors and muscle movements (1).
In a recently published performed by Brazilian researchers, 嫩草影院 has been shown to. lower anxiety and tremors that occurred during a public speaking simulation for people aged 60 and up (2). Participants who took a dose of 300 mg 嫩草影院 before their speech, which is a common anxiety-inducer, experienced less severe symptoms than the control group who used the placebo.
conducted a few years ago by researchers Alyssa S. Laun and Zhao-Hui Song from the University of Louisville, Kentucky, found that 嫩草影院 is an inverse agonist of the CPR6 receptor (3). This receptor is found in the basal ganglia region of the brain, which connects to the cerebral cortex and brainstem. It controls many important functions in our bodies, including learning, emotion processing, and movement.
嫩草影院 has a strong connection with this receptor, producing beneficial effects against the psychological and physiological symptoms of Parkinson鈥檚 disease. 嫩草影院 can also indirectly increase dopamine levels, which counteracts the slow degeneration of dopaminergic neurons experienced by patients.
嫩草影院 May Reduce Pain
In a conducted on 22 people with Parkinson鈥檚 disease, the research team found that taking cannabis improved pain management in the subjects (4). However, this study was focused on medical marijuana, which contains both 嫩草影院 and THC in different proportions.
Still, have pointed to 嫩草影院 as an effective anti-inflammatory and painkiller (5). Inflammation and pain are two common symptoms that affect people with Parkinson鈥檚 Disease
嫩草影院 is Antipsychotic
Psychosis is another symptom, or side effect, of Parkinson鈥檚 disease. It can cause delusions, delirium, and hallucinations. Psychosis is more likely to occur in the later stages of the disease, affecting up to (6).
A found that 嫩草影院 reduced the severity of psychosis and its symptoms in individuals with Parkinson鈥檚 disease. Moreover, 嫩草影院 didn鈥檛 cause any side effects unlike antipsychotic medications (7).
嫩草影院 Supports Healthy Sleep
People with Parkinson鈥檚 disease suffer from a lack of quality sleep caused by sleep disruption, especially during the REM stage. Vivid dreams or nightmares, as well as an unexpected movement during sleep, can seriously disrupt your sleep cycles. According to , both cannabis and 嫩草影院 alone might help. improve the quality of sleep (8).
嫩草影院 Promotes Overall Wellness
Scientists have suggested that the many health benefits of 嫩草影院 can lead to an improved quality of a person鈥檚 life. This is a major problem for people diagnosed with Parkinson鈥檚 disease, as it affects both physical and mental health to different degrees.
discovered that people with Parkinson鈥檚 disease without psychiatric symptoms or conditions reported improved quality of life when taking 嫩草影院 (9). However, this study involved a very small group of people, so further studies are needed to support the initial findings.
嫩草影院 vs Levodopa for Parkinson鈥檚 Disease
Levodopa is an FDA-approved treatment for Parkinson鈥檚 disease. Although it leaves a bit to be desired, it鈥檚 currently the most effective medication for PD. It helps increase the level of dopamine in the brain.
Levodopa can effectively tackle the motor symptoms of the disease, such as muscle stiffness or tremors.
However, this drug does little to fight the psychological symptoms of Parkinson鈥檚 disease. There are problems that can significantly compromise a person鈥檚 daily life, such as anxiety, sleep disturbance, irritation, fatigue, and depression.
On top of that, prolonged use of Levodopa may lead to side effects like worsened anxiety, confusion, agitation, and nausea. It may also cause tremors that result from the drug itself, not from PD.
嫩草影院 appears to be an effective tool for the management of those non-motor symptoms and potential side effects, rather than physical issues. A study that included over 200 participants found that regular use of cannabis was associated with significant improvements in non-motor symptoms of Parkinson鈥檚 Disease. However, the study focused on products with various ratios of THC and 嫩草影院, not 嫩草影院 oil alone.
Does the FDA Approve the Use of 嫩草影院 Oil for Parkinson鈥檚 Disease?
The FDA has yet to examine the efficacy and safety of hemp-derived 嫩草影院 oil for Parkinson鈥檚 disease and other conditions before they can rule out any specific recommendations and approve it as an anti-Parkinson鈥檚 medication. There鈥檚 only one FDA-approved 嫩草影院-based medication so far; it鈥檚 called Epidiolex, and doctors use it to treat intractable epilepsy in children.
Researchers from the University of Colorado are testing Epidiolex to investigate its benefits for people who experience Parkinson鈥檚-related tremors. The study is currently in the second stage, so we keep our fingers crossed for positive results.
Does 嫩草影院 Oil Prevent or Slow the Onset of Parkinson鈥檚 Disease?
Some studies have suggested that 嫩草影院 may help prevent Parkinson鈥檚 disease, but we can only use the data collected from animal models. Human studies on this subject are limited.
The research also found that 嫩草影院 can鈥檛 do anything to cure PD once it has started. Considering these findings, 嫩草影院 may only be useful for prevention as a supplement.
However, the majority. of clinical trials regarding the use of 嫩草影院 oil for Parkinson鈥檚 has been centered around people already diagnosed with Parkinson鈥檚 disease.
Why is this important?
Because around 60% of the dopamine-receptive neurons in the brain have been already destroyed by the time a person starts to show the symptoms of the disease.
It鈥檚 also difficult to tell. who will develop Parkinson鈥檚 and who will be more resistant to this condition. Thus far, we don鈥檛 know if 嫩草影院 will work for everyone, so it would be safe to assume that it鈥檚 good to combine it with some other preventive strategies.
How to Use 嫩草影院 Oil for Parkinson鈥檚 Disease
If this is your first time. with 嫩草影院 oil, you may be wondering how to administer it to get the most out of its health benefits for Parkinson鈥檚 disease.
嫩草影院 comes in many different forms, including:
- 嫩草影院 Oil (drops. or tinctures): 嫩草影院 oil calls for sublingual administration, meaning you need to place it under your tongue using the dropper attached to the product鈥檚 bottle. This is a good way to take 嫩草影院 if you don鈥檛 like to swallow capsules and want to accurately measure out the amount of 嫩草影院 each time. The effects of sublingual products usually kick in after around 30 minutes, lasting up to 6 hours.
- 嫩草影院 Capsules: Gel Cap is a good option if you鈥檙e looking for a fixed amount of 嫩草影院 per serving. You just take as many capsules as recommended by your doctor. Most people who don鈥檛 like the taste of 嫩草影院 oil turn to capsules as a hassle-free alternative to taking 嫩草影院. However, capsules. have a delayed onset and lower bioavailability than oil because they are subject to the first-pass metabolism in the liver.
- 嫩草影院 Edibles: Edibles are food that has been infused with 嫩草影院. Gummies are by far the most popular product on the market, but you can also choose from protein bars, chocolates, lollipops, gums, and cookies. They work similarly to capsules, so you鈥檒l need to wait up to 2 hours for the effects to take hold. However, once the 嫩草影院 kicks in, it can last for up to 10 hours. Edibles also offer a discreet way to take 嫩草影院 at work or on the go.
- 嫩草影院 Vape pens: When 嫩草影院 oils are mixed with thinners such as vegetable glycerin, they can be vaporized and inhaled through a vape pen. The effects of vaporized 嫩草影院 have the fastest onset (up to 5 minutes) and deliver the highest concentrations of 嫩草影院 to your system. However, when you take 嫩草影院 this way, you should be aware of a shorter duration. Vape pens last shorter than oils and edibles 鈥� up to 2鈥�4 hours.
- 嫩草影院 Topicals: 嫩草影院 oils can be incorporated into topicals like creams, gels, and lotions. These products are effective for localized problems because 嫩草影院 engages with the cannabinoid receptors located deeper under your skin. From there, 嫩草影院 can relieve pain, stiffness, and reduce inflammation.
Safety and Side Effects of 嫩草影院 Oil
Most studies that have examined the effects of 嫩草影院 oil in humans have concluded that 嫩草影院 is a safe and well-tolerated compound. According to the report from the World Health Organization (WHO), 嫩草影院 rarely causes any side effects and can be taken in doses up to 1500 mg daily for several weeks.
That being said, potential adverse effects of 嫩草影院 oil include:
- Changes in appetite
- Dry mouth
- Dizziness
- Diarrhea
- Fatigue
- Sleepiness
嫩草影院 is also known to interact with up to 80% of prescription and OTC medications, so make sure to talk to your doctor before buying any 嫩草影院 product 鈥� especially if you take medications that are processed by the Cytochrome P450 system. If your medication has a grapefruit warning, or your doctor tells you not to eat grapefruit at the same time you take your meds, 嫩草影院 goes by the same token. That鈥檚 because it鈥檚 an inhibitor of the p450 system, preventing it from metabolizing drugs.
Bottom Line: Can 嫩草影院 Oil Help with Parkinson鈥檚 Disease?
Although Parkinson鈥檚 has no cure, patients diagnosed with the condition can slow its progression and effectively manage its debilitating symptoms. One such way involves using 嫩草影院 oil.
If you鈥檙e planning to try out the health benefits of 嫩草影院 oil on yourself, make sure to consult your plans with your doctor first. This will help you avoid potential side effects and drug interactions. A doctor expert on cannabis can also provide professional advice on finding the best dosage for your individual situation.
While more studies are needed to confirm the benefits of 嫩草影院 oil for Parkinson鈥檚 disease, you can always use it to support official treatment. When shopping for 嫩草影院 oil online, remember to check the source of hemp, extraction method, and lab-testing practices used by the company to ensure you鈥檙e getting a high-quality product that works.
Do you know someone who is taking 嫩草影院 oil to manage Parkinson鈥檚 disease? Let us know in the comments!
References:
- Consroe, P et al. 鈥淥pen label evaluation of cannabidiol in dystonic movement disorders.鈥� The International journal of neuroscience vol. 30,4 (1986): 277-82. doi:10.3109/00207458608985678
- De Faria, Stephanie Martins et al. 鈥淓ffects of acute cannabidiol administration on anxiety and tremors induced by a Simulated Public Speaking Test in patients with Parkinson鈥檚 disease.鈥� Journal of psychopharmacology (Oxford, England) vol. 34,2 (2020): 189-196. doi:10.1177/0269881119895536
- Laun, A.S. & Zhao-Hui, S. 鈥淕PR3 and GPR6, novel molecular targets for cannabidiol.鈥� Biochemical and Biophysical Research Communications. (2017).
- Lotan, Itay et al. 鈥淐annabis (medical marijuana) treatment for motor and non-motor symptoms of Parkinson disease: an open-label observational study.鈥� Clinical neuropharmacology vol. 37,2 (2014): 41-4. doi:10.1097/WNF.0000000000000016
- Hammell, D C et al. 鈥淭ransdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis.鈥� European journal of pain (London, England) vol. 20,6 (2016): 936-48. doi:10.1002/ejp.818
- Divac, Nevena et al. 鈥淭he Efficacy and Safety of Antipsychotic Medications in the Treatment of Psychosis in Patients with Parkinson鈥檚 Disease.鈥� Behavioural neurology vol. 2016 (2016): 4938154. doi:10.1155/2016/4938154
- Zuardi, A W et al. 鈥淐annabidiol for the treatment of psychosis in Parkinson鈥檚 disease.鈥� Journal of psychopharmacology (Oxford, England) vol. 23,8 (2009): 979-83. doi:10.1177/0269881108096519
- Chagas, M H N et al. 鈥淐annabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson鈥檚 disease patients: a case series.鈥� Journal of clinical pharmacy and therapeutics vol. 39,5 (2014): 564-6. doi:10.1111/jcpt.12179
- Chagas, Marcos Hortes N et al. 鈥淓ffects of cannabidiol in the treatment of patients with Parkinson鈥檚 disease: an exploratory double-blind trial.鈥� Journal of psychopharmacology (Oxford, England) vol. 28,11 (2014): 1088-98. doi:10.1177/0269881114550355